中文名 | 1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐 |
英文名 | 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride |
别名 | EDC盐酸盐 1-乙基-3-(3-二甲基銨丙基)碳銨 1-(3-二甲氨基丙基)乙基碳二亚胺盐酸盐 乙基-(3-二甲基氨基丙基)碳酰二亚胺盐酸盐 1-(3-二甲胺丙基)-3-乙基碳二亚胺盐酸盐 1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐 1-乙基-3-(3-二甲氨丙基)碳二亚胺盐酸盐 1-乙基-(3-二甲基氨基丙基)碳酰二亚胺盐酸盐 1-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐 1-(3-二甲氨基丙基)-3-乙基-碳二亚胺盐酸盐 N-(3-二甲氨基丙基)-N'-乙基-碳二亚胺盐酸盐 1-乙基-3-(3-二甲基氨基丙基)碳酰二亚胺盐酸盐 1-(3-二甲基氨基丙基)-3-乙基碳化二亚胺盐酸盐 1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐(EDCI) |
英文别名 | WSC EDC·HCl EDC.HCL EDC.HCI EDC HCL EDC.HCl EDAC HCL EDAC.HCL EDAC,HCl EDC (WSC-HCl) AT test ,only COA Avanafil Impurity 40 Diquafosol Impurity m 1-[3-Dimethylamino propyl]-3-ethyl carbodiimide Hcl 3-ethylazo-N,N-dimethyl-propan-1-amine hydrochloride 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydroc (3-dimethylaminopropyl)ethyl-carbodiimidmonohydrochloride N-Ethyl-N-(3-dimethylaminopropyl)carbodiimide hydrochloride 3-[cyano(ethyl)amino]-N,N-dimethylpropan-1-aminium chloride N-(3-Dimethylaminopropyl)-N-ethylcarbodiimide hydrochloride 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide hydrochloride 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide Hydrochloride 1-Ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride N-(3-Dimethylaminopropyl)-N'-Ethylcarbodiimide Hydrochloride 1-Ethyl-3-(3-dimethyllaminopropyl)carbodiimide hydrochloride 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide hydrochloride 3-propanediamine,n'-(ethylcarbonimidoyl)-n,n-dimethyl-monohydrochloride 3-propanediamine,n'-(ethylcarbonimidoyl)-n,n-dimethyl-monohydrochloride N'-(Ethylkohlenstoffimidoyl)-N,N-dimethylpropan-1,3-diaminmonohydrochlorid |
CAS | 25952-53-8 |
EINECS | 247-361-2 |
化学式 | C8H18ClN3 |
分子量 | 191.7 |
InChI | InChI=1/C7H17N3.ClH/c1-4-8-9-6-5-7-10(2)3;/h4-7H2,1-3H3;1H/b9-8+ |
InChIKey | FPQQSJJWHUJYPU-UHFFFAOYSA-N |
密度 | 0.877g/mLat 20°C(lit.) |
熔点 | 110-115°C(lit.) |
沸点 | 209.2°C at 760 mmHg |
闪点 | 80.3°C |
水溶性 | Soluble |
蒸汽压 | 0.002Pa at 20℃ |
溶解度 | H2O: 溶解1 gm/10毫升,澄清至非常模糊,无色至非常微弱的黄色 |
折射率 | n20/D 1.461 |
存储条件 | -20°C |
稳定性 | 稳定,但对水分敏感。与强酸、强氧化剂、湿气不相容。 |
敏感性 | Hygroscopic |
外观 | 结晶性粉末 |
颜色 | White to off-white |
BRN | 5764110 |
物化性质 | 白色结晶。熔点111-113℃。 |
MDL号 | MFCD00012503 |
危险品标志 | C - 腐蚀性物品 Xi - 刺激性物品 |
风险术语 | R34 - 引起灼伤。 R36/37/38 - 刺激眼睛、呼吸系统和皮肤。 R41 - 对眼睛有严重伤害。 R37/38 - 刺激呼吸系统和皮肤+B52。 R20/21/22 - 吸入、皮肤接触及吞食有害。 |
安全术语 | S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。 S45 - 若发生事故或感不适,立即就医(可能的话,出示其标签)。 S37/39 - 戴适当的手套和护目镜或面具。 S36 - 穿戴适当的防护服。 |
危险品运输编号 | UN 2735 8/PG 3 |
WGK Germany | 3 |
RTECS | FF2200000 |
FLUKA BRAND F CODES | 1-3-10 |
TSCA | Y |
海关编号 | 29252000 |
Hazard Note | Irritant |
上游原料 | 3-((二甲基氨基)苯基硫代异氰酸酯 1-(3-二甲基氨基丙基)-3-乙基碳二亚胺 N,N-二甲基-1,3-二氨基丙烷 |
下游产品 | 2-氨基-5-溴苯甲酰胺 (2E,2'E)-3,3'-(1,4-亚苯基)双[2-丙烯酸 1-甲基环丙烷磺酰胺 |
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1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐,又称为EDC盐酸盐。以下是对其性质、用途、制法和安全信息的介绍:
性质:
1、EDC盐酸盐是一种白色结晶粉末,具有弱酸性。
2、它在水中易溶,在有机溶剂如醇、醚等中也溶解性良好。
3、EDC盐酸盐在室温下稳定。
用途:
1、EDC盐酸盐是一种常用的化学反应剂,在有机合成中具有广泛的应用。
2、作为活化剂:EDC盐酸盐可以与氨基酸或肽键发生反应,生成酰基化中间体,从而在肽合成和蛋白质修饰等领域中发挥重要作用。
3、作为偶联剂:EDC盐酸盐可以将酸和醇偶联形成酯键,用于合成酯化物、醚类和酰亚胺等化合物。
4、用于染料和颜料的合成。
制法:
EDC盐酸盐可以通过将EDC与盐酸反应得到。具体操作时,将EDC与足量的盐酸溶液混合,搅拌并加热反应,最后蒸发溶剂得到EDC盐酸盐的结晶。
安全信息:
1、EDC盐酸盐可能对皮肤、眼睛和呼吸道有刺激作用,应戴好防护手套、护目镜和口罩。
2、避免直接吸入或接触EDC盐酸盐的粉末。
3、在使用EDC盐酸盐时,应注意室内通风良好,避免吸入其挥发的气体。
4、在处理EDC盐酸盐时,应小心防止其被吞食或误食。
5、应存放在干燥、远离热源的地方,避免与氧化剂和易燃物接触。
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